Ignite Creation Date:
2024-05-06 @ 12:30 AM
Last Modification Date:
2024-10-26 @ 10:51 AM
Study NCT ID:
NCT01598961
Status:
COMPLETED
Last Update Posted:
2013-12-25
First Post:
2012-05-12
Brief Title:
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
Sponsor:
Samsung Medical Center
Organization:
Samsung Medical Center
Study Overview
Official Title:
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
Status:
COMPLETED
Status Verified Date:
2013-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVDHowever there have been no evidence of which degree of partial neuromuscular blockade should be performed or no neuromuscular blockade could be performed during LSR monitoring Therefore we performed a randomized controlled trial to evaluate the effect of different degree of partial neuromuscular blockade including no neuromuscular blockade on the LSR monitoring for MVD surgery
Detailed Description:
Hemifacial spasm develops by vascular compression of facial nerve at the root exit zone from brain stem Microvascular decompression MVD is known for its curative treatment Lateral spread response LSR is a kind of pathologic electromyographic EMG wave form which develops when facial nerve is compressed by vessel There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD
As neuromuscular blockade during LSR monitoring decreases the amplitude of EMG partial neuromuscular blockade is usually maintained during general anesthesia for MVD However there have been no evidence of which degree of partial neuromuscular blockade should be performed or no neuromuscular blockade could be performed during LSR monitoring Therefore we performed a randomized controlled trial to evaluate the effect of different degree of partial neuromuscular blockade including no neuromuscular blockade on the LSR monitoring for MVD surgery
As neuromuscular blockade during LSR monitoring decreases the amplitude of EMG partial neuromuscular blockade is usually maintained during general anesthesia for MVD However there have been no evidence of which degree of partial neuromuscular blockade should be performed or no neuromuscular blockade could be performed during LSR monitoring Therefore we performed a randomized controlled trial to evaluate the effect of different degree of partial neuromuscular blockade including no neuromuscular blockade on the LSR monitoring for MVD surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None