Ignite Creation Date:
2024-05-05 @ 10:00 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005255
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-05-25
Brief Title:
Ischemic Heart Disease Incidence and Indices of Body-fat Distribution
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2000-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To determine the association between ischemic heart disease incidence and anthropometric indices of body-fat distribution
Detailed Description:
BACKGROUND
Previous studies have demonstrated that abdominal obesity can be predictive of ischemic heart disease These prospective cohort studies employed simple indices of body-fat distribution such as waist-to-hip circumference ratio or subscapular skinfold Their similar results suggested that increased abdominal obesity conferred a two-fold increased risk of ischemic heart disease among middle-aged men The two proposed studies permitted testing of alternative fat-distribution indices which might be stronger risk factors for ischemic heart disease incidence than the waist-to-hip-ratio or the subscapular skinfold
DESIGN NARRATIVE
Two parallel case-control studies were conducted In both studies subjects were measured for girth skinfold abdominal sagittal diameter height and weight Analyses for both protocols considered men and women separately Possible confounders of the association between fat-distribution indices and ischemic heart disease were considered and if required adjusted for in multivariate analyses Possible confounders included race age tobacco use alcohol use diabetes social class hypertension cholesterol levels and physical activity levels
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Previous studies have demonstrated that abdominal obesity can be predictive of ischemic heart disease These prospective cohort studies employed simple indices of body-fat distribution such as waist-to-hip circumference ratio or subscapular skinfold Their similar results suggested that increased abdominal obesity conferred a two-fold increased risk of ischemic heart disease among middle-aged men The two proposed studies permitted testing of alternative fat-distribution indices which might be stronger risk factors for ischemic heart disease incidence than the waist-to-hip-ratio or the subscapular skinfold
DESIGN NARRATIVE
Two parallel case-control studies were conducted In both studies subjects were measured for girth skinfold abdominal sagittal diameter height and weight Analyses for both protocols considered men and women separately Possible confounders of the association between fat-distribution indices and ischemic heart disease were considered and if required adjusted for in multivariate analyses Possible confounders included race age tobacco use alcohol use diabetes social class hypertension cholesterol levels and physical activity levels
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL040844 | NIH | None | httpsreporternihgovquickSearchR01HL040844 |