Viewing Study NCT00108940



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Study NCT ID: NCT00108940
Status: COMPLETED
Last Update Posted: 2011-09-27
First Post: 2005-04-20

Brief Title: Siblings With Ischemic Stroke Study
Sponsor: Mayo Clinic
Organization: Mayo Clinic

Study Overview

Official Title: Siblings With Ischemic Stroke Study
Status: COMPLETED
Status Verified Date: 2011-09
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: SWISS
Brief Summary: The purpose of this study is to find the genes that increase the risk of developing an ischemic stroke using DNA samples collected from concordant stroke-affected sibling pairs
Detailed Description: Stroke is the third leading cause of death in the United States and a leading cause of acquired disability in adults Each year about 700000 people experience stroke in the country Ischemic stroke which constitutes about 80 percent of all strokes is a complex genetic disorder--the result of interactions between multiple genes and multiple environmental exposures Genes affecting cholesterol blood pressure clotting and other factors may increase the risk of ischemic stroke

In this clinical study investigators are studying groups of siblings in which at least two of the siblings have had an ischemic stroke The goal of this multi-center study is to find the genes that increase the risk of developing an ischemic stroke

To accomplish the aims of the study researchers are using DNA samples collected from concordant stroke-affected sibling pairs to determine if there are regions in the human genome associated with ischemic stroke or that may harbor stroke susceptibility genes

Two teaspoons of blood will be collected from each participant and submitted for genetic analysis Understanding the genetic predisposition to stroke could have major benefits for public health

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
R01NS039987 NIH None httpsreporternihgovquickSearchR01NS039987