Ignite Creation Date:
2024-05-06 @ 12:29 AM
Last Modification Date:
2024-10-26 @ 10:50 AM
Study NCT ID:
NCT01588197
Status:
COMPLETED
Last Update Posted:
2019-06-14
First Post:
2012-02-10
Brief Title:
Real-Time fMRI Feedback Effects on Pain Perception
Sponsor:
Medical University of South Carolina
Organization:
Medical University of South Carolina
Study Overview
Official Title:
Real-Time fMRI Feedback Effects on Pain Perception
Status:
COMPLETED
Status Verified Date:
2019-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether real-time functional magnetic resonance imaging may be a viable treatment for chronic pain in the future
Detailed Description:
Twenty-four healthy volunteers will undergo a series of four fMRI scanning sessions wherein thermal pain stimuli will be used to elicit activation of the pain neuro-matrix All participants will undergo thermal pain threshold testing before and after fMRI scan Participants will also rate the painfulness and unpleasantness of the thermal stimuli applied before fMRI and after fMRI All participants will be given prompts to apply a set of cognitive pain-control strategies Half of the participants will receive real-time fMRI feedback of activity in the Right Anterior Cingulate Cortex rACC and the other half will receive real-time fMRI feedback of activity in the Prefrontal Cortex PFC It is hypothesized that those receiving real-time feedback of brain activity thought to be involved with analgesic effects will demonstrate greater analgesia associated with the application of the cognitive control techniques after fMRI paradigm decreased pain intensity and unpleasantness ratings and increased thermal pain thresholds than those who are not given feedback before fMRI paradigm
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None