Ignite Creation Date:
2024-05-05 @ 11:40 AM
Last Modification Date:
2024-10-26 @ 9:11 AM
Study NCT ID:
NCT00102284
Status:
TERMINATED
Last Update Posted:
2010-01-27
First Post:
2005-01-26
Brief Title:
Neuromodulation and Language Acquisition Project Stage Ia
Sponsor:
University Hospital Muenster
Organization:
University Hospital Muenster
Study Overview
Official Title:
Improved Language Acquisition Through Neuromodulation Project Stage Ia
Status:
TERMINATED
Status Verified Date:
2006-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether levodopa pergolid rivastigmine or modafinil are effective in boosting semantic language acquisition in healthy subjects
Detailed Description:
Our prior work shows that d-amphetamine and the dopamine precursor levodopa markedly improve word learning success in healthy subjects In this randomized placebo-controlled double-blind clinical trial we probe whether a mixed d1d2 dopamine agonist pergolid or cholinergic neuromodulation rivastigmine or a general centrally arousing substance modafinil will yield a learning enhancement comparable to using levodopa in healthy subjects
Our results show that the dopamine agonist pergolide impaired learning in healthy subjects compared to placebo whereas cholinergic neuromodulation had no effect
Our results show that the dopamine agonist pergolide impaired learning in healthy subjects compared to placebo whereas cholinergic neuromodulation had no effect
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| IZKF Muenster Kne307404 | None | None | None |