Ignite Creation Date:
2024-05-06 @ 12:25 AM
Last Modification Date:
2024-10-26 @ 10:49 AM
Study NCT ID:
NCT01572467
Status:
COMPLETED
Last Update Posted:
2016-07-14
First Post:
2012-04-05
Brief Title:
Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors
Sponsor:
Childrens Oncology Group
Organization:
Childrens Oncology Group
Study Overview
Official Title:
DICER1 Mutations and miRNA in Ovarian and Testicular Sex Cord Stromal Tumors of Childhood
Status:
COMPLETED
Status Verified Date:
2016-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer
PURPOSE This research trial is studying genes in tumor samples from younger patients with ovarian or testicular sex cord stromal tumors
PURPOSE This research trial is studying genes in tumor samples from younger patients with ovarian or testicular sex cord stromal tumors
Detailed Description:
OBJECTIVES
To assess the role of DICER1 mutations and miRNA pathways in the etiology and progression of ovarian or testicular sex cord stromal tumors
OUTLINE Archived tumor tissue samples are analyzed for D1CER1 mutation and mRNA expression by reverse-transcriptase polymerase chain reaction RT-PCR and laser micro dissector Results are then correlated with medical data including age at diagnosis diagnosis pathology report presenting symptoms family history treatment outcome and length of follow-up when available
To assess the role of DICER1 mutations and miRNA pathways in the etiology and progression of ovarian or testicular sex cord stromal tumors
OUTLINE Archived tumor tissue samples are analyzed for D1CER1 mutation and mRNA expression by reverse-transcriptase polymerase chain reaction RT-PCR and laser micro dissector Results are then correlated with medical data including age at diagnosis diagnosis pathology report presenting symptoms family history treatment outcome and length of follow-up when available
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| COG-ARAR12B2 | OTHER | None | None |
| NCI-2012-00721 | REGISTRY | None | None |
| ARAR12B2 | OTHER | Childrens Oncology Group | None |