Ignite Creation Date:
2024-05-05 @ 11:39 AM
Last Modification Date:
2024-10-26 @ 9:11 AM
Study NCT ID:
NCT00103597
Status:
COMPLETED
Last Update Posted:
2005-10-20
First Post:
2005-02-11
Brief Title:
Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinsons Disease and Multiple System Atrophy
Sponsor:
Royal Brisbane and Womens Hospital
Organization:
Royal Brisbane and Womens Hospital
Study Overview
Official Title:
Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinsons Disease and Multiple System Atrophy
Status:
COMPLETED
Status Verified Date:
2005-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with Parkinsons Disease or Multiple System Atrophy MSA and symptoms of orthostatic hypotension are eligible for the study Each patient will have three weeks of conservative therapy three weeks of therapy with fludrocortisone and three weeks of therapy with domperidone Autonomic testing a symptom questionnaire bedside blood pressure testing and Unified Parkinson Disease Rating Scale UPDRS will be performed after each intervention
Detailed Description:
Enrolled patients ages 40-95 must have Parkinsons or MSA diagnosed by a neurologist and symptoms of orthostatic hypotension Each patient will fill out two validated questionnaires to determine if they are candidates for the study Baseline patient details such as their medications and UPDRS will be recorded Medications must be held stable during the period of the study
Each patient will then have three weeks of conservative therapy three weeks of therapy with fludrocortisone and three weeks of therapy with domperidone Autonomic testing a symptom questionnaire bedside blood pressure testing and UPDRS will be performed after each intervention
Each patient will then have three weeks of conservative therapy three weeks of therapy with fludrocortisone and three weeks of therapy with domperidone Autonomic testing a symptom questionnaire bedside blood pressure testing and UPDRS will be performed after each intervention
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2004135 | None | None | None |