Ignite Creation Date:
2025-12-25 @ 2:47 AM
Ignite Modification Date:
2025-12-26 @ 1:28 AM
Study NCT ID:
NCT01139333
Status:
COMPLETED
Last Update Posted:
2016-05-18
First Post:
2010-06-05
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Blood and Tumor Tissue Samples From Young Patients With Acute Myeloid Leukemia
Sponsor:
Children's Oncology Group
Organization:
Study Overview
Official Title:
Evaluation of Mer and Axl Expression in Acute Myeloid Leukemia Patient Samples
Status:
COMPLETED
Status Verified Date:
2016-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is studying blood and tumor tissue samples from young patients with acute myeloid leukemia.
PURPOSE: This research study is studying blood and tumor tissue samples from young patients with acute myeloid leukemia.
Detailed Description:
OBJECTIVES:
* To evaluate Mer and Axl expression in samples from pediatric patients with acute myeloid leukemia (AML).
* To determine if abnormal expression of Mer and Axl is associated with poor clinical characteristics (e.g., induction failure or relapse) of AML in these patients.
OUTLINE: This is a multicenter study.
Archived samples from pediatric patients with acute myeloid leukemia are analyzed for Mer and Axl expression by flow cytometry and western blot assays.
* To evaluate Mer and Axl expression in samples from pediatric patients with acute myeloid leukemia (AML).
* To determine if abnormal expression of Mer and Axl is associated with poor clinical characteristics (e.g., induction failure or relapse) of AML in these patients.
OUTLINE: This is a multicenter study.
Archived samples from pediatric patients with acute myeloid leukemia are analyzed for Mer and Axl expression by flow cytometry and western blot assays.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: