Ignite Creation Date:
2025-12-25 @ 2:38 AM
Ignite Modification Date:
2025-12-27 @ 10:10 PM
Study NCT ID:
NCT04645134
Status:
COMPLETED
Last Update Posted:
2022-11-16
First Post:
2020-11-22
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Physical Activity and Cognitive Function in Older Adults: A Novel Role for GPLD1
Sponsor:
Pennington Biomedical Research Center
Organization:
Study Overview
Official Title:
Physical Activity and Cognitive Function in Older Adults: A Novel Role for GPLD1
Status:
COMPLETED
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BrainFit
Brief Summary:
The investigators are conducting a cross-sectional, observational study to investigate whether plasma GPLD1 concentrations are associated with higher cognitive function and better brain structure and function in two groups of older adults with high or low levels of physical activity.
Detailed Description:
This is a cross-sectional, observational study which will enroll up to 28 healthy, older adults (65-85 y, BMI 20-35 kg/m2), and stratify by current self-reported physical activity level (equal inactive vs. equal highly active).
Aim 1: Investigate whether physical activity level is associated with GPLD1.
Aim 2: Investigate whether cognitive function and brain structure/function are associated with GPLD1.
Aim 1: Investigate whether physical activity level is associated with GPLD1.
Aim 2: Investigate whether cognitive function and brain structure/function are associated with GPLD1.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: