Ignite Creation Date:
2024-05-06 @ 12:04 AM
Last Modification Date:
2024-10-26 @ 10:44 AM
Study NCT ID:
NCT01484899
Status:
COMPLETED
Last Update Posted:
2013-07-08
First Post:
2011-11-28
Brief Title:
Smoking a Risk Factor for Pulmonary Arterial Hypertension
Sponsor:
University of Zurich
Organization:
University of Zurich
Study Overview
Official Title:
Smoking a Risk Factor for Pulmonary Arterial Hypertension A D-A-CH Pulmonary Hypertension Study Germany- Austria - Switzerland
Status:
COMPLETED
Status Verified Date:
2013-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DACH
Brief Summary:
Environmental factors may play a role in the genesis of pulmonary hypertension especially in endothelial dysfunction One widespread environmental factor associated with systemic endothelial dysfunction is cigarette smoke It may well be that cigarette smoking is not only a risk factor for systemic but also for pulmonary vascular diseases and herewith may interact with other risk factors such as a genetic background and associated conditions The existing studies which deal with this subject are only small single center case control studies providing less data Therefore a large European multicenter study is necessary
The investigators hypothesis are
a history of tobacco smoke exposure is highly prevalent in patients with PAH compared to the unaffected general population
a history of tobacco smoke exposure is more prevalent in patients with PAH compared to CTEPH
The investigators hypothesis are
a history of tobacco smoke exposure is highly prevalent in patients with PAH compared to the unaffected general population
a history of tobacco smoke exposure is more prevalent in patients with PAH compared to CTEPH
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None