Ignite Creation Date:
2024-05-06 @ 12:03 AM
Last Modification Date:
2024-10-26 @ 10:43 AM
Study NCT ID:
NCT01475552
Status:
COMPLETED
Last Update Posted:
2012-12-13
First Post:
2011-11-14
Brief Title:
Tailored Antiplatelet Therapy During Percutaneous Coronary Intervention in Patients With Diabetes Mellitus
Sponsor:
Seoul National University Bundang Hospital
Organization:
Seoul National University Bundang Hospital
Study Overview
Official Title:
The Effect of Point-of-care Platelet Function Assay Guided Antiplatelet Therapy on the Periprocedural Increase of Cardiac Enzymes
Status:
COMPLETED
Status Verified Date:
2012-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The researchers aimed to investigate the effect of point-of-care platelet function assay on the periprocedural cardiac enzyme elevation in patients with diabetes mellitus
All patients who are supposed to undergo coronary angiography were loaded with clopidogrel 300mg and aspirin 300mg at D-1 If patients were determined to implant coronary stent after diagnostic coronary angiography their platelet function is assayed with Verifynow-ADP Accumetrics If patients have 270 unit in the assay they are randomized to abciximab or control group After successful stent implantation cardiac enzymes CK-MB Troponin-I are followed at 8hr 16hr and 24hr Clinical outcomes including bleeding complications are assessed at 1 month
All patients who are supposed to undergo coronary angiography were loaded with clopidogrel 300mg and aspirin 300mg at D-1 If patients were determined to implant coronary stent after diagnostic coronary angiography their platelet function is assayed with Verifynow-ADP Accumetrics If patients have 270 unit in the assay they are randomized to abciximab or control group After successful stent implantation cardiac enzymes CK-MB Troponin-I are followed at 8hr 16hr and 24hr Clinical outcomes including bleeding complications are assessed at 1 month
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None