Ignite Creation Date:
2025-12-25 @ 2:32 AM
Ignite Modification Date:
2025-12-30 @ 2:10 PM
Study NCT ID:
NCT06957834
Status:
COMPLETED
Last Update Posted:
2025-05-05
First Post:
2025-05-02
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study
Sponsor:
National Skin Centre
Organization:
Study Overview
Official Title:
Randomised Double-blinded Split-face Controlled Study to Evaluate the Effectiveness of Eflornithine Hydrochloride Cream Compared to Topical Hydroquinone 2% Cream for the Treatment of Melasma.
Status:
COMPLETED
Status Verified Date:
2025-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to learn if Eflornithine hydrochloride cream works to treat melasma in adults, in comparison to Hydroquinone cream. It will also learn about the safety of Eflornithine hydrochloride cream. The main questions it aims to answer are:
* Does Eflornithine hydrochloride improve melasma assessment scores over a 3-month duration compared to Hydroquinone cream?
* What side effects might patients get while using Eflornithine hydrochloride cream?
Participants will:
* Apply both Eflornithine hydrochloride and Hydroquinone creams on separate halves of their faces every day for 3 months.
* Visit the clinic once at the 2-month mark and once at the 3-month mark for checkups and tests.
* Does Eflornithine hydrochloride improve melasma assessment scores over a 3-month duration compared to Hydroquinone cream?
* What side effects might patients get while using Eflornithine hydrochloride cream?
Participants will:
* Apply both Eflornithine hydrochloride and Hydroquinone creams on separate halves of their faces every day for 3 months.
* Visit the clinic once at the 2-month mark and once at the 3-month mark for checkups and tests.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?: