Ignite Creation Date:
2025-12-25 @ 2:25 AM
Ignite Modification Date:
2026-02-26 @ 9:58 AM
Study NCT ID:
NCT02909634
Status:
WITHDRAWN
Last Update Posted:
2018-08-10
First Post:
2016-09-14
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Combining Ostom-I With Abstats Sensors to Improve Prediction of Ostomy Output
Sponsor:
Cedars-Sinai Medical Center
Organization:
Study Overview
Official Title:
Combining Ostom-I With Abstats Sensors to Improve Prediction of Ostomy Output
Status:
WITHDRAWN
Status Verified Date:
2018-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
No devices currently available for study.
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Currently, the number of patients having either permanent or temporary stomas placed is increasing each year. Yet, patients with ostomy pouches often struggle with predicting when stool output will occur and how to plan around dynamic changes in intestinal activity. Ostom-I provides a real-time assessment of the volume in the ostomy bag, it does not predict when and how fast such output will occur. In this pilot study the investigators aim to gather normative AbStats and Ostom-I data in participants with an ostomy to improve prediction of stool output.
Aim 1: To gather normative AbStats and Ostom-I data in subjects with an ostomy to improve prediction of stool output.
Aim 2: Correlate the data from both wearable biosensors and test the predictive validity of AbStats in determining ostomy bag filling as measured by Ostom-I.
Aim 1: To gather normative AbStats and Ostom-I data in subjects with an ostomy to improve prediction of stool output.
Aim 2: Correlate the data from both wearable biosensors and test the predictive validity of AbStats in determining ostomy bag filling as measured by Ostom-I.
Detailed Description:
The Ostom-I device is a wireless, wearable biosensor that is approved by the U.S. Food and Drug Administration (FDA). The device is discrete, lightweight, and can be applied to an ostomy pouch in order to monitor the filling of the bag. It uses Bluetooth technology to send a signal to the participants smartphone and alerts the user when the ostomy bag is filling up so they can decide if and when to empty them.The second wearable biosensor is called "AbStats" and it provides an objective, real-time marker of intestinal motility, and is also FDA approved. It allows for continuous and automated analysis of intestinal vibrations.The study team will recruit consecutive inpatients undergoing colorectal surgery with ostomy placement. The surgeon will apply AbStats and Ostom-I upon completion of the operation. Device recordings will continue until discharge, or until the participant opts to remove the sensors as requested. Members of the research team who are blinded to sensor results will monitor and record clinical information including age, gender, race, and body mass index (BMI). The study team will record type of surgery performed, surgical approach, and any documented operative complications. The study team will prospectively monitor daily clinical assessments, including symptoms (nausea, vomiting, and abdominal pain), flatus, bowel movements, diet, ambulation, medication use, and length of hospitalization. All patients will receive a standardized feeding protocol as part of usual care. For Cedars-Sinai, the standard protocol initiates clear liquids on postoperative day (POD) zero, and rapid progression to a regular diet by the morning of POD#1 in patients without early clinical evidence of post-operative ileus (POI). Patients intolerant of the feeding protocol, including nausea or vomiting precluding advancement, or those that develop significant abdominal distension, will discontinue the feeding protocol. The surgical teams that make the decisions regarding diet changes will be blinded to device data.
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: