Ignite Creation Date:
2024-05-05 @ 11:37 AM
Last Modification Date:
2024-10-26 @ 9:11 AM
Study NCT ID:
NCT00099697
Status:
COMPLETED
Last Update Posted:
2009-12-11
First Post:
2004-12-17
Brief Title:
Biologic Effects of Dehydroepiandrosterone DHEA in Humans
Sponsor:
National Institute on Aging NIA
Organization:
National Institute on Aging NIA
Study Overview
Official Title:
Biologic Effects of DHEA in Humans
Status:
COMPLETED
Status Verified Date:
2004-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether DHEA replacement therapy decreases abdominal fat and improves insulin sensitivity
Detailed Description:
Studies on rats and mice have shown that the adrenal hormone dehydroepiandrosterone DHEA reduces abdominal visceral fat and protects against insulin resistance This study was done to learn if DHEA replacement therapy decreases abdominal obesity and improves insulin action in humans
Participants were randomly assigned to receive 50 mg per day of DHEA or a placebo at bedtime for 6 months Participants underwent magnetic resonance imaging MRI and oral glucose tolerance tests at the beginning and conclusion of the study Other tests included measurements of hormones and lipids
Participants were randomly assigned to receive 50 mg per day of DHEA or a placebo at bedtime for 6 months Participants underwent magnetic resonance imaging MRI and oral glucose tolerance tests at the beginning and conclusion of the study Other tests included measurements of hormones and lipids
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2M01RR000036 | NIH | None | httpsreporternihgovquickSearch2M01RR000036 |
| 5P60AG013629 | NIH | None | None |
| 5R01AG020076 | NIH | None | None |
| 5K23RR016191 | NIH | None | None |
| 3P30DK056341 | NIH | None | None |
| 5P60DK020579 | NIH | None | None |