Ignite Creation Date:
2024-05-05 @ 11:56 PM
Last Modification Date:
2024-10-26 @ 10:42 AM
Study NCT ID:
NCT01453842
Status:
COMPLETED
Last Update Posted:
2014-12-02
First Post:
2011-10-13
Brief Title:
Diet Oil Induced Stimulation of GLP-1
Sponsor:
University of Copenhagen
Organization:
University of Copenhagen
Study Overview
Official Title:
Diet Oil Induced Stimulation of GLP-1
Status:
COMPLETED
Status Verified Date:
2014-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Activation of G protein-coupled receptor GPR119 stimulates glucagon-like peptide-1 GLP-1release from the intestinal L-cells Previously administration of 2-oleyl-glycerol 2-OG to humans significantly increased plasma GLP-1 In the present study we want to test the effect in patients with type 2 diabetes The hypothesis is that we will expect to find a significant increased plasma GLP-1 following a meal containing of 2-OG when compared to meals containing of olive oil or carbohydrates alone
Detailed Description:
Activation of G protein-coupled receptor GPR119 stimulates glucagon-like peptide-1 GLP-1release from the intestinal L-cells Previously administration of 2-oleyl-glycerol 2-OG to humans significantly increased plasma GLP-1 In the present study we want to test the effect in patients with type 2 diabetes The hypothesis is that we will expect to find a significant increased plasma GLP-1 following a meal containing of 2-OG when compared to meals containing of olive oil or carbohydrates alone The aim of the study is to elucidate the effect of 2-OG diet oil on GLP-1 secretion in patients with type 2 diabetes and to explain the mechanism behind the known stimulation of GLP-1 release by dietary fat
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None