Ignite Creation Date:
2024-05-05 @ 11:51 PM
Last Modification Date:
2024-10-26 @ 10:40 AM
Study NCT ID:
NCT01432639
Status:
COMPLETED
Last Update Posted:
2013-06-06
First Post:
2011-09-07
Brief Title:
Effects of Exercise Training on Endothelial Function Inflammation Arterial Stiffness and Autonomic Function in CAD
Sponsor:
Universidade do Porto
Organization:
Universidade do Porto
Study Overview
Official Title:
Effects of Exercise Training on Endothelial Function Inflammation Arterial Stiffness and Autonomic Function in Coronary Artery Disease Patients
Status:
COMPLETED
Status Verified Date:
2013-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The main purposes of this study is to analyze in a randomized controlled trial the effects of an exercise-based cardiac rehabilitation program i on biomarkers of endothelial function ii on biomarkers of inflammation iii on autonomic function and iv on arterial stiffness in coronary artery disease patients CAD Additionally the investigators aim to analyze the v contribution of age and the changes in traditional risk factors to the modification of the endothelial dysfunction and inflammation and vi the contribution of the changes in inflammatory and endothelial function biomarkers to the modification of autonomic function and arterial stiffness
The investigators hypothesize that exercise training will improve the autonomic function arterial stiffness and mitigate the endothelial dysfunction and inflammation in CAD patients even in the absence of significant changes in traditional risk factors Thus the investigators expect with the present study to promote develop and expand the knowledge in this field by assessing the impact of exercise on a pool of markers that provide a wide picture of the pathophysiological processes underlying CAD
The investigators hypothesize that exercise training will improve the autonomic function arterial stiffness and mitigate the endothelial dysfunction and inflammation in CAD patients even in the absence of significant changes in traditional risk factors Thus the investigators expect with the present study to promote develop and expand the knowledge in this field by assessing the impact of exercise on a pool of markers that provide a wide picture of the pathophysiological processes underlying CAD
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None