Ignite Creation Date:
2024-05-05 @ 11:36 AM
Last Modification Date:
2024-10-26 @ 9:10 AM
Study NCT ID:
NCT00088712
Status:
COMPLETED
Last Update Posted:
2019-09-10
First Post:
2004-07-30
Brief Title:
Event Related Potentials in Infants and Adults
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Event Related Potentials From Infancy to Adulthood
Status:
COMPLETED
Status Verified Date:
2019-08-26
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will explore the development of visual perception and the brain activity that underlies it It will examine electrical activity in the brain while people are processing characteristics of the visual environment and how that processing might change with development
Infants who are within 2 weeks on either side of their 4-month birthday may be eligible for this study A parent of the child also participates
Parents who join the study are asked basic questions about their family such as its size and ethnic make-up their infants birth date complications of pregnancy or delivery and any health problems of the infant such as congenital developmental disorders or visual abnormalities
Each family is seen at the clinic one time for a 45-minute visit The infant is outfitted with an elastic net containing many small sensors that make contact with the scalp He or she is then shown pictures on a computer screen The sensors in the head net are connected to a computer that records the infants brain activity while the infant watches the pictures on the screen The head net is moistened with warm water before being applied and is not uncomfortable to wear Towels are available throughout the session to dry any excess moisture from the net
Infants who are within 2 weeks on either side of their 4-month birthday may be eligible for this study A parent of the child also participates
Parents who join the study are asked basic questions about their family such as its size and ethnic make-up their infants birth date complications of pregnancy or delivery and any health problems of the infant such as congenital developmental disorders or visual abnormalities
Each family is seen at the clinic one time for a 45-minute visit The infant is outfitted with an elastic net containing many small sensors that make contact with the scalp He or she is then shown pictures on a computer screen The sensors in the head net are connected to a computer that records the infants brain activity while the infant watches the pictures on the screen The head net is moistened with warm water before being applied and is not uncomfortable to wear Towels are available throughout the session to dry any excess moisture from the net
Detailed Description:
The major objective of this research is to better understand the response of the brain to significant stimulation in early and later development The proposed work is designed to examine infants childrens and adults especially mothers responses to salient features of the external environment To do so the present research studies the biological bases and behavioral significance of natural preferences and information processing The primary research strategy to be used consists of analyzing behavioral and brain responses to visual patterns In a laboratory procedure subjects will explore patterns and their brain electrical activity will be measured simultaneously with an electronic analysis system In specific five experiments of visual attention in human infants and 1 experiment in adults are proposed In the first experiment with infants babies are hypothesized to look longer at more saturated colors in a second experiment babies are hypothesized to look longer at gratings aligned along the vertical and horizontal orthogonals than along the obliques Because saturated colors and orthogonal stimulation elicit greater activity in visual system neurons and greater amplitude evoked potentials than desaturated colors or oblique stimulation respectively these two experiments explore the hypothesis that the simple visual stimuli to which infants preferably attend are those that are particularly appropriate in stimulating the geniculostriate or primary visual system In the third experiment we plan to trace the ontogeny of the mature brain response to whole patterns as opposed to parts of patterns In a fourth experiment we intend to compare region-specific activity when the surface features of a familiarized visual target change to that when its location changes In the fifth experiment we examine individual differences in the power metrics associated with attention to visual stimuli in relation to individual differences in their corresponding behavior coded by observers In an experiment with children and adults we will explore brain responses and their localization in to pictures of familiar and unfamiliar faces
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 04-CH-0250 | None | None | None |