Ignite Creation Date:
2024-05-05 @ 11:49 PM
Last Modification Date:
2024-10-26 @ 10:40 AM
Study NCT ID:
NCT01425684
Status:
COMPLETED
Last Update Posted:
2021-05-03
First Post:
2011-08-28
Brief Title:
Brain Circuits in Schizophrenia and Smoking
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Brain Circuits in Schizophrenia and Smoking
Status:
COMPLETED
Status Verified Date:
2021-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The principle aim of the project is to identify the key brain circuits associated with smoking and especially smoking in high risk population The investigators hope that the study will provide concrete biomarkers for new therapeutic development and ultimately reducing the smoking related health burden
Detailed Description:
There are several studies and hypotheses to be tested This project includes 1 a cross-sectional study design that measures brain imaging smoking clinical diagnosis and symptoms cognitive functional assessments distress tolerance and genetic information which is also the baseline for the longitudinal study and 2 a longitudinal study design for smoking cessation option for 1 year in some smokers and a longitudinal follow-up for all available subjects
During the baseline portion of the study subjects are expected to complete clinical symptom assessments a computer challenge task to measure distress tolerance MRI scan role-play test to measure cognitive and functional abilities and blood draw Subjects who are eligible will participate in the longitudinal follow-up study where the research team will call subjects regularly regarding smoking related information smoking risk and treatment options
During the baseline portion of the study subjects are expected to complete clinical symptom assessments a computer challenge task to measure distress tolerance MRI scan role-play test to measure cognitive and functional abilities and blood draw Subjects who are eligible will participate in the longitudinal follow-up study where the research team will call subjects regularly regarding smoking related information smoking risk and treatment options
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01DA027680 | NIH | None | httpsreporternihgovquickSearchR01DA027680 |