Ignite Creation Date:
2025-12-25 @ 2:14 AM
Ignite Modification Date:
2025-12-26 @ 6:24 PM
Study NCT ID:
NCT04681560
Status:
COMPLETED
Last Update Posted:
2020-12-23
First Post:
2020-04-18
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Impact of Platinum-based Cancer Treatment on Endothelial Function
Sponsor:
I.M. Sechenov First Moscow State Medical University
Organization:
Study Overview
Official Title:
The Effect of Polychemotherapy on Endothelial Function Ans Vessel Age in Cancer Patients.
Status:
COMPLETED
Status Verified Date:
2019-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this research we investigate endothelial function in cancer patients who received platinum based chemotherapy.
Detailed Description:
The goal of the study is to evaluate endothelial function in patients with platinum-based versus non-platinum-based chemotherapy.
Endothelial function was evaluated via Angioscan( the apparatus that evaluate the stiffness of vessels by pulse wave velocity) and serum levels of endothelial nitric oxide synthase (ENOS),endothelin1.
Patients with gastrointestinal, ovarian, bladder and brest cancer would be included.
Patients with malignancies were followed-up from 2 weeks to 3 month after start of chemotherapy, Medical records and hospital databases were searched for all the patients treated with different chemotherapy treatment for any kind of cancer.
Endothelial function was evaluated via Angioscan( the apparatus that evaluate the stiffness of vessels by pulse wave velocity) and serum levels of endothelial nitric oxide synthase (ENOS),endothelin1.
Patients with gastrointestinal, ovarian, bladder and brest cancer would be included.
Patients with malignancies were followed-up from 2 weeks to 3 month after start of chemotherapy, Medical records and hospital databases were searched for all the patients treated with different chemotherapy treatment for any kind of cancer.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: