Ignite Creation Date:
2024-05-05 @ 11:35 AM
Last Modification Date:
2024-10-26 @ 9:10 AM
Study NCT ID:
NCT00081562
Status:
COMPLETED
Last Update Posted:
2008-02-21
First Post:
2004-04-15
Brief Title:
Genetics of Ankylosing Spondylitis
Sponsor:
National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS
Organization:
National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS
Study Overview
Official Title:
Family Studies of the Genetics of Ankylosing Spondylitis
Status:
COMPLETED
Status Verified Date:
2008-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Ankylosing spondylitis AS is a chronic inflammatory disease that affects the joints between the vertebrae of the spine and the joints between the spine and the pelvis The purpose of this study is to collect information and blood samples from patients with AS and their relatives for use in genetic studies
Detailed Description:
AS is a chronic inflammatory disease that eventually causes the affected vertebrae to fuse or grow together The cause of AS is unknown but genetic factors seem to play a role Risk factors include a family history of ankylosing spondylitis and male gender
This study will collect patient information and blood samples from affected patients and when available both parents of the affected patients of 400 families with children fulfillling the modified New York criteria for AS Diagnosis of AS will be verified by patient questionnaire medical record review and pelvic radiographs Information from these patients will be used to search the human genome for disease-associated loci andor genes This study will also utilize contributions of investigators who have conducted recent clinical or genetic research in AS at 10 academic medical centers throughout North America the North American Spondylitis Consortium or NASC
This study will collect patient information and blood samples from affected patients and when available both parents of the affected patients of 400 families with children fulfillling the modified New York criteria for AS Diagnosis of AS will be verified by patient questionnaire medical record review and pelvic radiographs Information from these patients will be used to search the human genome for disease-associated loci andor genes This study will also utilize contributions of investigators who have conducted recent clinical or genetic research in AS at 10 academic medical centers throughout North America the North American Spondylitis Consortium or NASC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 5R01AR046208-05 | NIH | None | None |
| NASC | US NIH GrantContract | None | httpsreporternihgovquickSearch5R01AR046208-05 |