Ignite Creation Date:
2024-05-05 @ 11:39 PM
Last Modification Date:
2024-10-26 @ 10:37 AM
Study NCT ID:
NCT01383304
Status:
UNKNOWN
Last Update Posted:
2016-05-12
First Post:
2011-06-22
Brief Title:
Aspirin Response in High Risk Patients With Coronary Artery Disease
Sponsor:
University of Aarhus
Organization:
University of Aarhus
Study Overview
Official Title:
Is a Reduced Biochemical Response to Aspirin Associated With Increased Cardiovascular Morbidity and Mortality in High Risk Patients With Coronary Artery Disease
Status:
UNKNOWN
Status Verified Date:
2015-05
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Previous studies indicate that patients with cardiovascular disease have a variable response to aspirin Despite treatment with aspirin a large number of patients suffer a myocardial infarction This has given rise to the phenomenon aspirin low-responsiveness Laboratory aspirin low-responsiveness can be defined as the failure of aspirin to inhibit platelet production of thromboxane A2 or inhibit thromboxane-dependent platelet aggregation Whether a low platelet response to aspirin results in an increased risk of future thrombotic events is of great clinical significance but is still unknown
The investigators hypothesize that patients with a reduced response to aspirin determined by platelet aggregation using the apparatus Verify Now Aspirin and Multiplate have a higher risk of thrombosis
The purpose of this study is to investigate whether a higher incidence of cardiovascular events is found in patients with coronary artery disease CAD having a reduced biochemical response to aspirin compared with CAD patients having a normal biochemical response to aspirin In addition to CAD all patients have at least one of the following risc factors previous myocardial infarction type 2 diabetes mellitus andor renal insufficiency
The investigators hypothesize that patients with a reduced response to aspirin determined by platelet aggregation using the apparatus Verify Now Aspirin and Multiplate have a higher risk of thrombosis
The purpose of this study is to investigate whether a higher incidence of cardiovascular events is found in patients with coronary artery disease CAD having a reduced biochemical response to aspirin compared with CAD patients having a normal biochemical response to aspirin In addition to CAD all patients have at least one of the following risc factors previous myocardial infarction type 2 diabetes mellitus andor renal insufficiency
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None