Ignite Creation Date:
2024-05-05 @ 11:35 AM
Last Modification Date:
2024-10-26 @ 9:10 AM
Study NCT ID:
NCT00084201
Status:
COMPLETED
Last Update Posted:
2006-11-30
First Post:
2004-06-08
Brief Title:
Interactions Between Cranberry Juice and Antibiotics Used to Treat Urinary Tract Infections
Sponsor:
National Center for Complementary and Integrative Health NCCIH
Organization:
National Center for Complementary and Integrative Health NCCIH
Study Overview
Official Title:
Cranberry Interactions With Anti-Infectious Agents
Status:
COMPLETED
Status Verified Date:
2006-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of study is to determine whether cranberry juice interacts with antibiotics used to treat urinary tract infections UTIs
Detailed Description:
Although evidence of its effectiveness is limited cranberry juice is widely used to prevent urinary tract infections UTIs However recent studies have shown that cranberry juice may affect the way the body absorbs and metabolizes antibiotics used to treat UTIs This study will determine whether concurrent cranberry juice administration lowers the urinary concentrations of two commonly used antibiotics amoxicillin and cefaclor
This study will involve children being treated for UTIs and adults without UTIs All of the children will continue their prescribed amoxicillincefaclor treatment After 7 to 10 days of antibiotic treatment the children will be assigned to receive either cranberry juice for 2 days or no additional treatment Urine samples will be collected from all child participants before and after the administration of cranberry juice to examine the excretion of the antibiotics
Adult participants will receive two different doses of amoxicillin with or without cranberry juice Blood and urine samples will be collected to evaluate the effect of cranberry juice on the absorption and elimination of amoxicillin
This study will involve children being treated for UTIs and adults without UTIs All of the children will continue their prescribed amoxicillincefaclor treatment After 7 to 10 days of antibiotic treatment the children will be assigned to receive either cranberry juice for 2 days or no additional treatment Urine samples will be collected from all child participants before and after the administration of cranberry juice to examine the excretion of the antibiotics
Adult participants will receive two different doses of amoxicillin with or without cranberry juice Blood and urine samples will be collected to evaluate the effect of cranberry juice on the absorption and elimination of amoxicillin
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None