Ignite Creation Date:
2024-05-05 @ 11:35 PM
Last Modification Date:
2024-10-26 @ 10:36 AM
Study NCT ID:
NCT01366170
Status:
COMPLETED
Last Update Posted:
2016-05-19
First Post:
2011-06-02
Brief Title:
Biomarker Expression in Samples From Young Patients With Anaplastic Large Cell Lymphoma
Sponsor:
Childrens Oncology Group
Organization:
Childrens Oncology Group
Study Overview
Official Title:
Expression of T Immunoregulatory Proteins in ALK Anaplastic Large Cell Lymphoma ALCL
Status:
COMPLETED
Status Verified Date:
2016-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer it may also help doctors predict how patients will respond to treatment
PURPOSE This research trial studies biomarker expression in tissue samples from young patients with anaplastic large cell lymphoma
PURPOSE This research trial studies biomarker expression in tissue samples from young patients with anaplastic large cell lymphoma
Detailed Description:
OBJECTIVES
To determine the expression of immunoregulatory proteins including CD4 FOXP3 and CD276 in anaplastic large cell lymphoma ALCL
To correlate the expression of these proteins with the levels of anaplastic lymphoma kinase ALK autoantibodies in patient of ANHL0131
OUTLINE Archived tissue microarray samples are analyzed by mass spectrometry and validated by Western blotting flow cytometry and IHC
To determine the expression of immunoregulatory proteins including CD4 FOXP3 and CD276 in anaplastic large cell lymphoma ALCL
To correlate the expression of these proteins with the levels of anaplastic lymphoma kinase ALK autoantibodies in patient of ANHL0131
OUTLINE Archived tissue microarray samples are analyzed by mass spectrometry and validated by Western blotting flow cytometry and IHC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| ANHL11B1 | OTHER | Childrens Oncology Group | None |
| COG-ANHL11B1 | OTHER | None | None |
| NCI-2011-02860 | REGISTRY | None | None |