Ignite Creation Date:
2024-05-05 @ 11:31 PM
Last Modification Date:
2024-10-26 @ 10:34 AM
Study NCT ID:
NCT01346761
Status:
COMPLETED
Last Update Posted:
2016-04-14
First Post:
2011-04-29
Brief Title:
Risk Education and Assessment for Cancer Heredity
Sponsor:
University of Utah
Organization:
University of Utah
Study Overview
Official Title:
Bridging Geographic Barriers Remote Cancer Genetic Counseling for Rural Women
Status:
COMPLETED
Status Verified Date:
2016-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
REACH
Brief Summary:
Individuals living in geographically underserved areas encounter considerable barriers to access of quality cancer genetic services Although in-person genetic counseling has generally been accepted as the standard of care the use of telecommunications to deliver clinical genetic services may help reduce this disparity in access to such services However before the widespread adoption of telephone-delivered cancer genetic services occurs it is critical to analyze the efficacy and safety of this mode of communication This two-group randomized equivalencynon-inferiority trial will determine whether telephone-based cancer genetic counseling is an acceptable alternative to the traditional in-person mode among women who have a personal or family history of breast andor ovarian cancer strong enough to warrant genetic counseling and testing This studys findings will provide important information to cancer centers and cancer control policies about the safety efficacy and costs of delivering telephone-based clinical cancer genetic services for geographically challenged women at risk for having Breast Cancer susceptibility gene BRCA 12 mutations
Detailed Description:
Following confirmation of eligibility and completion of baseline surveys participants will be randomly assigned to one of the study arms by the project coordinator using a computer-generated allocation algorithm on the basis of a randomization blocks method using four six or eight participants in each block
In-person and telephone counseling will be delivered by the same board-certified genetic counselors using a guideline-concordant semi-structured protocol that will allow for personalization of counseling
Participants randomly assigned to telephone counseling will be mailed packets that include a sealed envelope containing an educational brochure about hereditary breast and ovarian cancer genetic counseling with visual aids At the time of their session participants will review the brochure and genetic counselors will use visual aids to explain breast-ovarian cancer genetics Women receiving in-person counseling will be given the same materials during their session at the community clinic
For women who elect to have testing those who have telephone counseling will be sent a genetic test kit those who have in-person counseling will have the option of giving a sample immediately at the clinic or will be given a test kit with the same instructions as those in the telephone-counseling group
When BRCA test results become available participants will be offered individual post-test counseling with the same genetic counselor who conducted the pretest session
In-person and telephone counseling will be delivered by the same board-certified genetic counselors using a guideline-concordant semi-structured protocol that will allow for personalization of counseling
Participants randomly assigned to telephone counseling will be mailed packets that include a sealed envelope containing an educational brochure about hereditary breast and ovarian cancer genetic counseling with visual aids At the time of their session participants will review the brochure and genetic counselors will use visual aids to explain breast-ovarian cancer genetics Women receiving in-person counseling will be given the same materials during their session at the community clinic
For women who elect to have testing those who have telephone counseling will be sent a genetic test kit those who have in-person counseling will have the option of giving a sample immediately at the clinic or will be given a test kit with the same instructions as those in the telephone-counseling group
When BRCA test results become available participants will be offered individual post-test counseling with the same genetic counselor who conducted the pretest session
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01CA129142-01A2 | NIH | None | httpsreporternihgovquickSearch1R01CA129142-01A2 |