Ignite Creation Date:
2024-05-05 @ 11:33 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00075348
Status:
COMPLETED
Last Update Posted:
2012-03-15
First Post:
2004-01-09
Brief Title:
Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome
Sponsor:
National Institutes of Health Clinical Center CC
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Genetic Mutation Analysis In A VHL Population
Status:
COMPLETED
Status Verified Date:
2012-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE The identification of gene mutations in individuals who have or are at risk for von Hippel-Lindau syndrome may allow doctors to better determine the genetic processes involved in the development of cancer
PURPOSE This genetic study is finding gene mutations in participants with von Hippel-Lindau syndrome or who are at risk for developing von Hippel-Lindau syndrome
PURPOSE This genetic study is finding gene mutations in participants with von Hippel-Lindau syndrome or who are at risk for developing von Hippel-Lindau syndrome
Detailed Description:
OBJECTIVES
Obtain laboratory identification and confirmation of research results for gene mutations in participants previously enrolled in NCI-99-C-0053 who have von Hippel-Lindau VHL syndrome or who are at risk for VHL syndrome
Determine genotype status in these participants
OUTLINE Participants submit a blood or buccal sample for genetic mutation analysis Participants may receive genetic counseling andor the results of genetic testing if desired
PROJECTED ACCRUAL A maximum of 260 participants will be accrued for this study
Obtain laboratory identification and confirmation of research results for gene mutations in participants previously enrolled in NCI-99-C-0053 who have von Hippel-Lindau VHL syndrome or who are at risk for VHL syndrome
Determine genotype status in these participants
OUTLINE Participants submit a blood or buccal sample for genetic mutation analysis Participants may receive genetic counseling andor the results of genetic testing if desired
PROJECTED ACCRUAL A maximum of 260 participants will be accrued for this study
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| CDR0000302478 | None | None | None |
| 03-C-0148 | None | None | None |