Ignite Creation Date:
2024-05-05 @ 11:33 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00074555
Status:
COMPLETED
Last Update Posted:
2016-01-06
First Post:
2003-12-16
Brief Title:
Registry for African Americans With Early Rheumatoid Arthritis
Sponsor:
National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS
Organization:
National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS
Study Overview
Official Title:
Consortium for the Longitudinal Evaluation of African Americans With Early Rheumatoid Arthritis CLEAR
Status:
COMPLETED
Status Verified Date:
2016-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CLEAR
Brief Summary:
The purpose of this study is to better understand the causes of rheumatoid arthritis RA particularly in African Americans
Detailed Description:
RA is an autoimmune disease in which the bodys immune system attacks its own tissues It occurs in all races and ethnic groups and affects about two to three times as many women as men Variations in certain genes that play a role in the immune system are associated with a tendency to develop RA Some individuals without these genetic variations may develop this disease while others who possess the variations never develop RA Scientists believe that some environmental factors may play a part in triggering the disease process in people whose genetic makeup makes them susceptible to RA This registry of African Americans with early RA will provide clinical and x-ray data and DNA to help scientists analyze genetic and nongenetic factors that might predict disease course and outcomes of RA in this population
Participants in this registry will be enrolled in the study until they reach 5 years in their disease duration For example if a participant enters the study after 1 year of having RA he or she will continue for 4 years Participants will have three office visits screening 3 years disease duration and 5 years disease duration at which they will complete questionnaires and have blood samples taken x-rays of their hands and feet and DEXA scans Between office visits the study coordinator will call participants every 6 months to update any changes in medications or health problems
Participants in this registry will be enrolled in the study until they reach 5 years in their disease duration For example if a participant enters the study after 1 year of having RA he or she will continue for 4 years Participants will have three office visits screening 3 years disease duration and 5 years disease duration at which they will complete questionnaires and have blood samples taken x-rays of their hands and feet and DEXA scans Between office visits the study coordinator will call participants every 6 months to update any changes in medications or health problems
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NIAMS-106 | None | None | None |