Ignite Creation Date:
2024-05-05 @ 11:32 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00075920
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2004-01-11
Brief Title:
Technical Development of Strain Rate Echocardiography
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Technical Development of Strain Rate Echocardiography
Status:
COMPLETED
Status Verified Date:
2007-10-17
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will examine heart function using two imaging techniques - echocardiography ultrasound and magnetic resonance imaging MRI - to evaluate newly developed software for echocardiograph machines MRI and ultrasound both provide images of the heart structure and function MRI uses a magnetic field and radio waves to obtain the pictures while echocardiography uses sound waves
Patients with any form of heart disease and healthy volunteers 21 years of age and older may be eligible for this study Candidates must be and able to undergo magnetic resonance imaging and must not have an irregular heart rhythm heart valve disease a pacemaker defibrillator implant insulin pump or other metallic implant
Participants will have two ultrasound examinations and two magnetic resonance imaging examinations as described below All the tests will be completed within 24 to 48 hours
Echocardiography
For this test a small probe is passed over the chest Sound waves emitted from the probe bounce off the heart and are beamed back into the echo machine where they are recorded The sonographer does a baseline test which is evaluated by the physician Then after a 10- to 20-minute break portions of the test are repeated The entire exam takes about 2 hours
Magnetic Resonance Imaging
For MRI the subject lies on a table that slides into a long doughnut-shaped scanner A small tube is placed in a vein in the hand or arm to give fluids and to infuse gadolinium a contrast material that brightens the images Heart rate and blood pressure are monitored during the study which takes about 3 hours
Patients with any form of heart disease and healthy volunteers 21 years of age and older may be eligible for this study Candidates must be and able to undergo magnetic resonance imaging and must not have an irregular heart rhythm heart valve disease a pacemaker defibrillator implant insulin pump or other metallic implant
Participants will have two ultrasound examinations and two magnetic resonance imaging examinations as described below All the tests will be completed within 24 to 48 hours
Echocardiography
For this test a small probe is passed over the chest Sound waves emitted from the probe bounce off the heart and are beamed back into the echo machine where they are recorded The sonographer does a baseline test which is evaluated by the physician Then after a 10- to 20-minute break portions of the test are repeated The entire exam takes about 2 hours
Magnetic Resonance Imaging
For MRI the subject lies on a table that slides into a long doughnut-shaped scanner A small tube is placed in a vein in the hand or arm to give fluids and to infuse gadolinium a contrast material that brightens the images Heart rate and blood pressure are monitored during the study which takes about 3 hours
Detailed Description:
The purpose of this protocol is to study the reproducibility of strain rate SR echocardiography in normal volunteers and patients with cardiovascular disease Tissue Doppler ultrasound is a technology which has been validated for the analysis of global and regional left ventricular function and strain and SR measurements are derived from tissue Doppler imaging TDI data Over the last few years several improvements in echo machine hardware and software have facilitated the rapid acquisition and analysis of tissue Doppler data and therefore strain and strain rate information has become easily accessible Recent publications have demonstrated the usefulness of these techniques in the analysis of systolic and diastolic function of the left ventricle and in the detection of regional wall motion and ischemia Several protocols recently initiated in the Cardiovascular Branch involve echocardiographic imaging and include applications of TDI as their primary or secondary endpoints Therefore the purpose of this protocol is to allow development of standardized acquisition and analysis methods of TDI for our cardiology protocols and to evaluate the reproducibility of TDI SR and strain measurements
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 04-H-0082 | None | None | None |