Ignite Creation Date:
2024-05-05 @ 11:10 PM
Last Modification Date:
2024-10-26 @ 10:30 AM
Study NCT ID:
NCT01277055
Status:
UNKNOWN
Last Update Posted:
2011-01-14
First Post:
2011-01-13
Brief Title:
MRI Perfusion Imaging at 3Tx Compared to Invasive FFR Measurements
Sponsor:
Heart Center Bogenhausen
Organization:
Heart Center Bogenhausen
Study Overview
Official Title:
MRI Perfusion Imaging at 3T With TX Parallel RF Technology to Identify Myocardial Ischemia Compared to Invasive FFR Measurements
Status:
UNKNOWN
Status Verified Date:
2011-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Vision MRT
Brief Summary:
Coronary artery disease CAD has a great significance concerning prevalence and mortality in the western world It is usually diagnosed by catheterization and coronary arteries are visually assessed by the examiner Thus having a great spectrum of interobserver differences especially when it comes to intermediate lesions The gold standard to assess the haemodynamic significance is the measurement of the myocardial fractional flow reserve FFR The FAME-study Tonino De Bruyne et al 2009 was able o show that additional FFR- measurements in patients with intermediate lesions could significantly reduce stent implementation and consequently mortality However this method is not used in daily routine and is available only in a fraction of catheter labs worldwide Taking this into account decision finding especially in intermediate lesions remains difficult
One major step to simplify the invasive approach concerning intermediate lesions would be to establish a non-invasive procedures which localizes the coronary vessel to intervene ahead catheterization
Do to steady technical development cardiac MRI has become a powerful tool which is able to determine myocardial vitality perfusion and function In particular the new generation of 3 Tesla multi transmit MR with its higher field strength and better spatial resolution seems to be able to show first pass myocardial perfusion more precise With this new technology prefixed to cardiac catheterization clinical relevant information can be made accessible and thus reduce the number of unnecessary implemented stents
One major step to simplify the invasive approach concerning intermediate lesions would be to establish a non-invasive procedures which localizes the coronary vessel to intervene ahead catheterization
Do to steady technical development cardiac MRI has become a powerful tool which is able to determine myocardial vitality perfusion and function In particular the new generation of 3 Tesla multi transmit MR with its higher field strength and better spatial resolution seems to be able to show first pass myocardial perfusion more precise With this new technology prefixed to cardiac catheterization clinical relevant information can be made accessible and thus reduce the number of unnecessary implemented stents
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None