Event Group
Event Groups are part of the Adverse Events Module within the Results Section. They provide a way to organize and summarize adverse event data by grouping related events together.
Each Event Group typically represents a category or class of adverse events and includes statistical information such as the number of participants affected and at risk for different event types: deaths, serious events, and other events.
Event Group path is as follows:
Study -> Results Section -> Adverse Events Module -> Event Group
Event Group
Ignite Creation Date:
2025-12-24 @ 1:32 PM
Ignite Modification Date:
2025-12-25 @ 12:33 PM
NCT ID:
NCT02152995
Group ID:
EG001
Title:
Cohort B (Iodine I-124 PET/CT, Trametinib, Iodine I-131)
Description:
Patients without BRAF/RAS gene mutations undergo iodine I-124 PET/CT on day 5 of week 1. Beginning day 6, patients receive trametinib PO daily for 4 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo second iodine I-124 PET/CT on week 5. If I-124 PET/CT shows enough iodine absorption, patients may receive iodine I-131 PO and continue receiving trametinib for another 2 days. If I-124 shows that the thyroid is not absorbing iodine, patients have the option to be assigned to Cohort C.
Computed Tomography: Undergo iodine I-124 PET/CT
Iodine I 124: Undergo iodine I-124 PET/CT
Iodine I-131: Given PO
Laboratory Biomarker Analysis: Correlative studies
Pharmacodynamic Study: Correlative studies
Positron Emission Tomography: Undergo iodine I-124 PET/CT
Trametinib: Given PO
Deaths Number Affected:
1
Deaths Number At Risk:
None
Serious Number Affected:
1
Serious Number At Risk:
9
Other Number Affected:
9
Other Number At Risk:
9
Study:
NCT02152995
Results Section:
NCT02152995
Adverse Events Module:
NCT02152995