Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:23 AM
Ignite Modification Date:
2025-12-25 @ 1:23 AM
NCT ID:
NCT06754293
Eligibility Criteria:
Inclusion Criteria:1. Pathologically confirmed hormone receptor-positive breast cancer (stage I, II, III).
2\. Initiation of treatment with aromatase inhibitors (e.g., anastrozole, letrozole, exemestane).
3\. Postmenopausal women, including those with surgically induced menopause. 4. Clear consciousness, no cognitive or communication impairments, and able to comply with the intervention.
5\. Informed consent obtained, with voluntary participation in the study. 6. Bone and joint symptoms with a Brief Pain Inventory (BPI) score of ≥3, or presence of at least one of the following risk factors: elevated bone turnover markers, reduced vitamin D levels, increased inflammatory cytokines, elevated C-reactive protein, or elevated rheumatoid factor.
7\. Not participating in any physical therapy or exercise-based interventions that may interfere with this study.
\-
Exclusion Criteria:
\- 1. Recurrence of breast cancer or distant metastasis. 2. Presence of other malignancies. 3. Diagnosed rheumatoid arthritis, bone and joint trauma, or other severe bone and joint diseases.
4\. Bone mineral density T-score \<-2.5. 5. Presence of absolute contraindications to exercise.
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT06754293
Study Brief:
Protocol Section:
NCT06754293