Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:22 AM
Ignite Modification Date:
2025-12-25 @ 1:22 AM
NCT ID:
NCT05686993
Eligibility Criteria:
Inclusion Criteria:
* Confirmed PA, as demonstrated by a positive screening test and internationally endorsed confirmatory test (saline suppression test, captopril challenge test)
* Adults \> 18 years of age
* Able and willing to give informed consent
Exclusion Criteria:
* Uncontrolled hypertension requiring use of MRA
* Unwilling or unable to give consent
* Below age 18 or above age 90 years
* Allergy to cinnarizine or nifedipine or their excipients
* Existing use of cinnarizine or nifedipine for an alternative indication
* Breastfeeding or pregnant women
* Diagnosis of Parkinson's disease
* Severe hepatic or renal insufficiency
* Concurrent use of sedating central nervous system (CNS) depressants or rifampicin
* Porphyria
* Cardiogenic shock, clinically significant aortic stenosis, unstable angina, within one month of a myocardial infarction
* Previous gastro-intestinal or oesophageal obstruction or ileostomy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
90 Years
Study:
NCT05686993
Study Brief:
Protocol Section:
NCT05686993