Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:59 AM
Ignite Modification Date:
2025-12-24 @ 11:59 AM
NCT ID:
NCT07149961
Eligibility Criteria:
Inclusion Criteria:
* Adults aged 18 to 80 years.
* Confirmed diagnosis of ST-Elevation Myocardial Infarction (STEMI). Symptom onset within 12 hours, or within 12 to 72 hours in cases with an indication for primary percutaneous coronary intervention (PPCI).
* Receiving standard-of-care medical therapy according to current guidelines, including:
Dual antiplatelet therapy. Angiotensin-Converting Enzyme Inhibitors (ACE-i) or Angiotensin Receptor Blockers (ARBs).
Statins. Beta-blockers.
Exclusion Criteria:
* Regular prior use of curcumin supplementation.
* Hemodynamic instability or severe dyspnoea with clinical signs of congestion (elevated jugular venous pressure, pulmonary rales affecting \>1/3 of lung fields, hepatomegaly, ascites, or peripheral oedema).
* History of prior myocardial infarction, previous percutaneous coronary intervention, or coronary artery bypass graft surgery.
* Known hypersensitivity to curcumin or piperine.
* Active malignancy.
* Chronic infections (e.g., hepatitis, tuberculosis, or HIV).
* Estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73 m² or rapidly declining renal function.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT07149961
Study Brief:
Protocol Section:
NCT07149961