Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:16 AM
Ignite Modification Date:
2025-12-25 @ 1:16 AM
NCT ID:
NCT01820793
Eligibility Criteria:
Inclusion Criteria:
* Inclusion Criteria: Acute pyelonephritis without severity symptoms with a positive urine culture for ESBL-producing E. coli (cefoxitin-sensitive); antibiotic treatment should have been prescribed before inclusion for the empirical treatment of pyelonephritis, providing it is not active in vitro against ESBL-producing E. coli strain.
* Presenting at least a functional sign of urinary infection (dysuria, cloudy urine, pain on urination, pelvic or lumbar pain)
* Temperature \>38 ° or \< 36° during the infectious episode
* Imaging of the urinary ways realized within (echography) 72 hours preceding the inclusion.
Exclusion Criteria:
* Pregnant women
* β-lactam allergy;
* antimicrobial therapy active in vitro against ESBL-producing E.coli pyelonephritis instituted prior to enrolment;
* life expectancy \<30 days;
* creatinine clearance \<30 ml/min;
* patient under guardianship or without healthcare coverage.
* Sign of sepsis severe or septic shock
* Major cognitive confusions
* Patients having refused to give her consent form in writing
* Not membership in a national insurance scheme or in the Universal Health Coverage (CMU).
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
18 Years
Study:
NCT01820793
Study Brief:
Protocol Section:
NCT01820793