Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:15 AM
Ignite Modification Date:
2025-12-25 @ 1:15 AM
NCT ID:
NCT07097493
Eligibility Criteria:
Inclusion Criteria:
* 18-80 years of age
* Receiving primary total knee arthroplasty
* Patients receiving a spinal anesthetic with ropivacaine and fentanyl
* American Society of Anesthesiology (ASA) category 1 to 3
Exclusion Criteria:
* Revision of Total Knee Arthroplasty
* Opioid use in the prior 6 months \> 40 mg oxycodone equivalents per day or long-acting opioids as determined by the Prescription Drug Monitoring Program (PDMP)
* Patients planned to receive general anesthesia
* Patients planned to receive a spinal other than ropivacaine
* History of peripheral neuropathy
* Poorly controlled diabetes (Hgb A1C \>8)
* Allergies or contraindications to study medications: acetaminophen, celecoxib (including sulfa), methocarbamol, midazolam, fentanyl, bupivacaine, dexamethasone, acetaminophen, buprenorphine, NSAIDs, clonidine, epinephrine, and liposomal bupivacaine.
* Unable to provide informed consent
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07097493
Study Brief:
Protocol Section:
NCT07097493