Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:14 AM
Ignite Modification Date:
2025-12-25 @ 1:14 AM
NCT ID:
NCT01932593
Eligibility Criteria:
Inclusion Criteria:
Participation in the phase I safety and feasibility 'Study of Intravenous Autologous Marrow in Multiple Sclerosis' (SIAMMS) (REC reference number number 05/Q1704/137 Clin Pharmacol Ther. 2010 Jun;87(6):679-85)
Exclusion Criteria:
* pregnancy, breastfeeding or lactation
* bone marrow insufficiency
* history of lymphoproliferative disease or previous total lymphoid irradiation immune deficiency
* history of current or recent (\<5 years) malignancy
* chronic or frequent drug-resistant bacterial infections or presence of active - infection requiring antimicrobial treatment
* frequent and/or serious viral infection
* systemic or invasive fungal disease within 2 years of entry to study
* significant renal, hepatic, cardiac or respiratory dysfunction
* contraindication to anaesthesia
* bleeding or clotting diathesis
* current or recent (within preceding 12 months) immunomodulatory therapy other than corticosteroid therapy
* treatment with corticosteroids within the preceding 3 months
* radiation exposure in the past year other than chest / dental x-rays
* previous claustrophobia
* the presence of any implanted metal or other contraindication to MRI participation in another experimental study or treatment within previous 24 months
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
25 Years
Maximum Age:
80 Years
Study:
NCT01932593
Study Brief:
Protocol Section:
NCT01932593