Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:11 AM
Ignite Modification Date:
2025-12-25 @ 1:11 AM
NCT ID:
NCT05653193
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of CPA
* Started antifungal treatment for CPA within the last 8 weeks and received no antifungals for CPA in the 8 weeks prior
* Chest CT scan available within the 6 months prior to enrolment
* Individuals of child bearing potential agree to have pregnancy test an use highly effective contraception
Exclusion Criteria:
* Moderate to severe liver dysfunction (Child-Pugh Class B or C)
* Renal failure (eGFR \<30 mL/min)
* Clinically diagnosed active depression
* Active tuberculosis or non-tuberculous mycobacterial (NTM) lung disease
* Acute infection or other event within the preceding 4 weeks which, as assessed by the investigators, might interfere with the assessment of response to treatment
* Use of any interferon formulation within the preceding six months
* Active viral hepatitis infection
* Pregnancy or breastfeeding
* Immunosuppression (\>15mg prednisolone/day for at least four weeks or equivalent) within the preceding six months
* Inability to self-administer subcutaneous medications AND lack of a carer who can administer
* Participants lacking capacity to consent
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05653193
Study Brief:
Protocol Section:
NCT05653193