Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:08 AM
Ignite Modification Date:
2025-12-25 @ 1:08 AM
NCT ID:
NCT06063993
Eligibility Criteria:
Inclusion Criteria:
* The subjects are adults aged ≥18 years old
* admitted tothe intensive care unit of the National Hepatologyand Tropical Medicine Research Institute (NHTMRI).
* Patients with clinical signs of hemodynamic instability i.e. a systolic blood pressure \< 90 mmHg or decrease in systolic blood pressure \> 40 mmHg, signs of organ hypoperfusion as oliguria \< 0.5ml/Kg/hour.
Exclusion Criteria:
* If there is known peripheral vascular disease
* or ≥ 2 vasopressors with the maximum doses
* or in the presence of nail polish as readings from pulse oximeter will be distortedin these cases
* or if there is contraindication for PLR as uncontrolled hemodynamic status
* intracranial hypertension
* severe chronic obstructive pulmonary disease
* broncho-alveolar fistula
* severe emphysema
* and those with pre-existing comorbidities including severe left and right ventricular dysfunction, severe pulmonary hypertension
* severe obesity (BMI \>40 kg/m2)
* pregnancy.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06063993
Study Brief:
Protocol Section:
NCT06063993