Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:06 AM
Ignite Modification Date:
2025-12-25 @ 1:06 AM
NCT ID:
NCT01467193
Eligibility Criteria:
Inclusion Criteria:
* Male and female patients \>18 years old
* Capable to exercise for 120 minutes on a treadmill
* Willingness to participate in the study and to give written consent.
* Normal ECG during ergometry
* Specific for Athletes: VO2max\> 50 ml/kg/min
* Specific for GHD patients: no GH substitution in the last 6 months
* Specific for sedentary controls: Matched the GHD patients for age, gender, BMI and waist
Exclusion Criteria
* Abnormal liver or renal function
* Active neoplasia
* Severe cardiovascular disease (unstable coronary artery disease, heart failure NYHA III-IV)
* Haemophilia
* Inability to exercise
* Contraindications to exposure to a 3 T magnetic field
* Abnormal ECG during ergometry
* Women in childbearing age unless on a continuous contraceptive therapy or surgically sterilized
* Depression, psychosis and other severe personality disorders
* Pregnant women
* Excessive alcohol consumption (\>60g/d) or drug abuse
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT01467193
Study Brief:
Protocol Section:
NCT01467193