Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:06 AM
Ignite Modification Date:
2025-12-25 @ 1:06 AM
NCT ID:
NCT01632293
Eligibility Criteria:
Inclusion Criteria:
* Confirmed diagnosis of MS
* If on immunomodulatory therapy, subjects have to have been on that therapy for at least 6 months prior to the start of the study.
* Medically stable
* Able to follow complex directions as determined by a score of less than or equal to 1 on a subset of questions taken from the NIH Stroke scale
* Normal passive range of motion at the hips, knees, and ankles with minimum to no pain
Exclusion Criteria:
* Evidence of other neurological deficit that could interfere, such as previous stroke or muscle disease
* Congestive heart failure
* MS exacerbation within 8 weeks of study start
* MS exacerbation affecting CST or DC-ML tracts
* peripheral artery disease with claudication
* cancer
* pulmonary or renal failure
* unstable angina
* uncontrolled hypertension (greater than 190/110 mmHg)
* orthopedic or pain conditions
* history of kidney disease, due to potential of gadolinium reactions leading to nephrogenic systemic fibrosis (NSF)
* because pregnancy may change the MRI signals that we are studying, we have chosen not to enroll pregnant women in this study
Healthy controls have the same age and exclusion criteria as people with multiple sclerosis except that they must have normal neurological function
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
75 Years
Study:
NCT01632293
Study Brief:
Protocol Section:
NCT01632293