Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:06 AM
Ignite Modification Date:
2025-12-25 @ 1:06 AM
NCT ID:
NCT06286293
Eligibility Criteria:
Inclusion Criteria:
All subjects
* Sufficient command of the Dutch language
* In possession of a driver's license with any driving experience throughout life
* Age 18 to 65
bvYOD subjects
* Probable diagnosis of young-onset dementia (before 65 years old), confirmed after interdisciplinary consensus meeting in which interviews, neuropsychological examination, neurological and psychiatric assessments, neuro-imaging, blood samples, and in some cases FDG/PIB-PETscans, CSF biomarkers or genetic counseling were discussed.
* Nosological diagnosis of bvFTD or bvAD
Non-bvYOD subjects
* Probable diagnosis of young-onset dementia (before 65 years old), confirmed after interdisciplinary consensus meeting in which interviews, neuropsychological examination, neurological and psychiatric assessments, neuro-imaging, blood samples, and in some cases FDG/PIB-PETscans, CSF biomarkers or genetic counseling were discussed.
* YOD subtypes other dan bvFTD or bvAD, such as amnestic variant AD.
Frontal brain injury subjects
\- Neurological patients with frontal brain injury (e.g. traumatic brain injury, stroke or brain tumor patients).
Exclusion Criteria:
All subjects
* Suffering from severe motion sickness; motion sickness is a risk factor for simulator sickness
YOD subjects:
\- Presence of premorbid severe neurological or psychiatric pathology, non-related to dementia.
Frontal brain injury subjects:
\- Presence of serious psychiatric disorders or other neurological comorbidities.
Healthy control subjects:
* Presence of serious psychiatric disorders
* History of neurological disorders, which may interfere with cognitive functioning (e.g. recent concussion, previous subarachnoid or intracerebral haemorrhage, intracranial tumours, epilepsy, ischemic stroke).
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT06286293
Study Brief:
Protocol Section:
NCT06286293