Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:05 AM
Ignite Modification Date:
2025-12-25 @ 1:05 AM
NCT ID:
NCT04103593
Eligibility Criteria:
Inclusion Criteria:
* Veteran living with HIV and under care at VAMC
* 50 years of age and older
* Stable antiretroviral therapy (same ARV medications within 3 months)
* At least one HIV-1 PCR \< 20 c/ml (viral load) within prior 6 months
Exclusion Criteria:
* History of AIDS defining illnesses (within 6 months; CDC Criteria)
* Myocardial infarction (within 3 months)
* Exertional or unstable angina (current chest pain that limits activity)
* Severe congestive heart failure (EF \< 20% in last year or NYHA Classification III or IV)
* Uncontrolled hypertension (SBP \>180 \&/or DBP \> 110 mm Hg)
* Therapy with beta blockers or non-dihydropyridine calcium channel blocker (within 1 month)
* Screening EKG with ischemia, complex arrhythmia, or high-grade block (per Minnesota Code)
* Poorly controlled DM within prior 1 month (FBS\>180 mg/dl, RBS \> 299 mg/dl, or HbA1C \> 10)
* Receiving treatment for cancer except skin cancer (within 3 months)
* Peripheral vascular disease with claudication
* Severe arthritis limiting ambulation
* Neurologic disease limiting ambulation (requiring assist device)
* End stage liver disease (decompensated liver disease)
* Chronic renal failure (requiring dialysis)
* Severe pulmonary disease (home O2, admission for dyspnea or pneumonia within 1 month)
* Use of systemic steroids (testosterone or glucocorticoids) or growth hormone (within 6 months)
* Dementia (based on Evaluation to Consent)
* Signs or symptoms of any medical comorbidity that would preclude exercise testing or training
* Exercise on routine basis (structured aerobic exercise \> 3 times per week) within 1 month
* Past medical history of COPD or emphysema AND mMRC score =4
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT04103593
Study Brief:
Protocol Section:
NCT04103593