Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 1:02 AM
Ignite Modification Date:
2025-12-25 @ 1:02 AM
NCT ID:
NCT06817993
Eligibility Criteria:
Inclusion Criteria:
* Between ages 13-17
* Depression screening scores on the MFQ-C in the mild (MFQ = 12-25; N = 20) or moderate-to-severe range (MFQ ≥25; N=30)
* Possess their own smartphone to complete web-based ecological momentary assessments (EMA) using WebDataExpress.
* use social media apps (e.g. Instagram, twitter, reddit, discord, YouTube, etc.) at least 3 times a week, on average, per teen report
Exclusion Criteria:
* Presence of a serious neurological or medical condition, by parent report
* Unable to read or speak English or cognitive impairment preventing ability to complete assessments.
* Hearing impairment preventing ability to hear and understand instructions conveyed via headphones in the MRI scanner
* Possible pregnancy, as determined by participant report
* Presence of probable substance use disorder, as determined by participant report
* Presence of MRI contraindications (e.g., dental braces, history of metallic foreign objects in body such as aneurysm clips or other devices or questionable history of metallic fragments, claustrophobia, or a weight of above 300 lbs)
* Taking medications that affect the central nervous system other than antidepressants (stable dose allowed due to high rates of use among teens with depressive symptoms) or stimulants if required 36 hours before the scan.
* Completion of Chatroom Interact Task or TBO Task in prior studies
* Screening positive on the Autism Spectrum Screening Questionnaire, or screening positive on the Youth Inventory-4/ for a potential psychotic disorder or substance use disorder.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
13 Years
Maximum Age:
17 Years
Study:
NCT06817993
Study Brief:
Protocol Section:
NCT06817993