Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:56 AM
Ignite Modification Date:
2025-12-25 @ 12:56 AM
NCT ID:
NCT03288467
Eligibility Criteria:
Inclusion Criteria:
* Patient willingness to participate in the study
* Mature permanent mandibular first and second molars requiring primary root canal treatment
* Diagnosis of pulpal necrosis, as confirmed by negative response to cold and electrical tests; and absence of bleeding on entering the pulp chamber
* Radiographic evidence of periapical radiolucency (minimum size ≥ 2.0 × 2.0 mm)
* Patient's age more than 18 years
Exclusion Criteria
* Positive history of antibiotic use within past one month of the treatment.
* Positive history of analgesic use within the past 3 days.
* Patients who are pregnant, diabetic, immunocompromised, had serious medical illness or required antibiotic premedication
* Patients with pockets ≥4mm or having marginal or furcal bone loss due to periodontitis
* Teeth that are not suitable for rubber dam isolation
* Previously accessed teeth and/or with procedural errors
* Unrestorable tooth, fractured/ perforated roots, inflammatory root resorption
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
47 Years
Study:
NCT03288467
Study Brief:
Protocol Section:
NCT03288467