Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:54 AM
Ignite Modification Date:
2025-12-25 @ 12:54 AM
NCT ID:
NCT00142467
Eligibility Criteria:
Inclusion Criteria:
* Unresectable or metastatic hepatocellular carcinoma
* Measurable tumors
* Adequate hepatic function: total bilirubin \< 3.0mg/dl; AST \< 7x ULN
* Adequate bone marrow function: ANC \> 1,000/mm3; platelets \> 75,000/mm3
* INR \< 1.5 for those who are not on anticoagulation
* Up to two prior chemotherapy regimens for hepatocellular carcinoma
* 18 years of age or older
* ECOG performance status of 0-1
* Life expectancy of \> 12 weeks
Exclusion Criteria:
* Clinically apparent central nervous system metastases or carcinomatous meningitis
* Uncontrolled serious medical or psychiatric illness
* Pregnant or lactating women
* Current or recent (within 4 weeks of first study infusion) participation in experimental study drug
* Uncontrolled hypertension
* Significant proteinuria
* Serious, non-healing wound, ulcer, or bone fracture
* Evidence of bleeding diathesis or coagulopathy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00142467
Study Brief:
Protocol Section:
NCT00142467