Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:53 AM
Ignite Modification Date:
2025-12-25 @ 12:53 AM
NCT ID:
NCT01086267
Eligibility Criteria:
Inclusion Criteria:
* Subjects with K-RAS (codon 12 or 13) or B -RAF (V600E) mutation positive advanced or metastatic colorectal cancer who have relapsed or are refractory to 2 or more standard systemic anticancer regimes for metastatic disease, or are intolerant to existing therapies.
* Histologic or cytologic confirmation of the diagnosis.
* Eastern Cooperative Oncology Group (ECOG) ≤ 1
* Adequate organ \& marrow function.
Exclusion Criteria:
* Uncontrolled or significant cardiovascular disease.
* Phase 2: Prior therapy with a RAF inhibitor.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01086267
Study Brief:
Protocol Section:
NCT01086267