Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:45 AM
Ignite Modification Date:
2025-12-25 @ 12:45 AM
NCT ID:
NCT02590367
Eligibility Criteria:
Inclusion Criteria:
1. All cases have been diagnosed with colorectal cancer by pathology;
2. Patients who received no chemotherapy before should receive oxaliplatin-based chemotherapy(FOLFOX4,FOLFOX6,XELOX) ;
3. Patients of 18-70 years old have no serious heart,liver,kidney and hematopoietic disfunction,life expectancy of over 3 months and KPS more than 60;
4. Patients with no positive sign in neurological examination,and no drug allergy history or diabetes;
5. Volunteered to participate and signed informed consent,patients can not receive radiotherapy,acupuncture and moxibustion or other treatment during the experiment.
Exclusion Criteria:
1. Not accordant with the inclusion criteria;
2. Patients who have used herbal within 4 weeks before registration;
3. Patients who have serious heart,liver,kidney and hematopoietic disfunction;
4. Patients of central nervous system disease;
5. Patients of cervical spondylopathy,lumbar disc protrusion,diabetes and uremia which can potentially cause peripheral neuropathy;
6. Nerve compression caused by tumor metastasis or peripheral neuropathy caused by electrolyte disturbances,diabetes,alcohol disease and other disorder;
7. Long-time using of thiazide diuretic and foxglove;
8. Patients of poisoning,infection and radiotherapy which induced peripheral neuropathy or receiving medicine which can cause peripheral neuropathy;
9. Patients who can hardly take Chinese Medicine with severe diarrhea,vomiting or intestinal obstruction ;
10. Uncontrolled psychosis;
11. Women of pregnancy ,preparing pregnant, or lactation;
12. Alcohol and drug abuse;
13. Allergic constitution or allergy to experiment drugs.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT02590367
Study Brief:
Protocol Section:
NCT02590367