Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:45 AM
Ignite Modification Date:
2025-12-25 @ 12:45 AM
NCT ID:
NCT04328467
Eligibility Criteria:
Inclusion Criteria:
\- A healthcare worker at high risk for COVID-19 exposure (defined below):
* Persons primarily working in emergency departments (physicians, nurses, ancillary staff, triage personnel)
* Persons primarily working in intensive care units (physicians, nurses, ancillary staff, respiratory therapists)
* Persons performing aerosol generating procedures (i.e. anesthesiologists, nurse anesthetists (CRNAs)
* First responders (i.e. EMTs, paramedics)
Exclusion Criteria:
* Active COVID-19 disease
* Prior COVID-19 disease
* Current fever, cough, shortness of breath
* Allergy to chloroquine or hydroxychloroquine
* Prior retinal eye disease
* Known Chronic Kidney disease, Stage 4 or 5 or dialysis
* Known glucose-6 phosphate dehydrogenase (G-6-PD) deficiency
* Weight \<40 kg
* Prolonged QT syndrome
* Current use of hydroxychloroquine, chloroquine, or cardiac medicines of flecainide, amiodarone, digoxin, procainamide, or propafenone
* Current use of medications with known significant drug-drug interactions: artemether, lumefantrine, mefloquine, tamoxifen, or methotrexate.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04328467
Study Brief:
Protocol Section:
NCT04328467