Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:44 AM
Ignite Modification Date:
2025-12-25 @ 12:44 AM
NCT ID:
NCT00355667
Eligibility Criteria:
Inclusion Criteria:
* Clinical diagnosis of heart failure based on a slight modification of the Framingham criteria as previously described within 6 months before the entry
* Current status of heart failure is NYHA II or III.
* Currently, loop diuretic(s) is (are) administered.
* No change in baseline therapy and symptoms of heart failure within a month
Exclusion Criteria:
* Current symptomatic hypotension
* Hypertension that has not been controlled to the satisfaction of the investigator
* Hemodynamically significant (in the investigators opinion) LV outflow tract obstruction (due to either aortic stenosis or ventricular hypertrophy)
* Acute coronary syndrome
* Primary pulmonary hypertension or pulmonary hypertension not due to LV dysfunction
* Serious cerebrovascular disease
* Acute myocardial infarction within the last 3 months
* Patients who require intravenous inotropes
* Cerebrovascular accident within the last 3 months
* Percutaneous coronary intervention or open heart surgery within the last 3 months
* On the waiting list for percutaneous coronary intervention or open heart surgery
* Serum creatinine \> 2.5 mg/dl
* Serious liver disease
* Any change in cardiovascular drug therapy within a month prior to randomization
* History of chronic obstructive pulmonary disease or restrictive lung disease
* Diabetes mellitus that has not been well controlled (fasting blood glucose\>200 mg/dl、HbA1c \> 8%)
* Any life-threatening acute disease
* Patients with implantable cardiac defibrillator
* Other diseases likely to cause death or serious disability during the period of the study
* Patients unable to walk without personal aid
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Study:
NCT00355667
Study Brief:
Protocol Section:
NCT00355667