Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:39 AM
Ignite Modification Date:
2025-12-25 @ 12:39 AM
NCT ID:
NCT02461667
Eligibility Criteria:
Inclusion Criteria:
* All the subjects were systemically healthy
* subjects with sites having CAL ≥ 3 mm, PPD ≥ 5 mm,
* vertical bone loss ≥ 3 mm on intraoral periapical radiographs (IOPA) and
* subjects with no history of periodontal intervention in the last 6 months.
Exclusion Criteria:
* patients with systemic diseases like cardiovascular disease
* diabetes or HIV infection or on medications like corticosteroids which may impede the healing in periodontal tissues.
* pregnant/lactating females
* tobacco users
* alcoholics
* patients with unsatisfactory oral hygiene (plaque index greater than 1.5)
* teeth having gingival recession, caries involving pulp, intrabony defect present interproximally, grade 2/3 mobility
* Furthermore, patients allergic to Metformin and alendronate or those taking Metformin and alendronate systemically were excluded.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
25 Years
Maximum Age:
55 Years
Study:
NCT02461667
Study Brief:
Protocol Section:
NCT02461667