Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-25 @ 12:38 AM
Ignite Modification Date:
2025-12-25 @ 12:38 AM
NCT ID:
NCT05363267
Eligibility Criteria:
Inclusion Criteria:
* NF1 diagnosis based on NIH Consensus Conference Criteria and/or genetic testing
* Measurable cutaneous neurofibromas (cNFs) with or without plexiform NF
* Aged 18 years or older at the time of written consent
* Voluntary signed written consent obtained before the performance of any study-related procedure not part of normal medical care
Exclusion Criteria:
* Concurrent treatment with selumetinib or other MAPK, MEK or mTOR inhibitors, other targeted therapies, chemotherapy or radiation
* Conditions requiring systemic immunosuppression
* Swallowing difficulties or strong gag reflex which may interfere with study compliance
* Any comorbidities that may affect study participation in the judgement of enrolling investigator
* Psychiatric illness, cognitive challenges, social situations, or other circumstances that would limit compliance with study requirements, per judgment of the enrolling investigator
* Treatment with high phenolic olive oil or curcumin within six months of study entry
* Known pregnancy or anticipated conception during the 1 year study period
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05363267
Study Brief:
Protocol Section:
NCT05363267